Humanin

Also known as: HN, Mitochondrial-derived peptide

Longevity & CellularEmerging evidenceResearch peptide — not FDA-approvedHow we rate evidence

Summary

A mitochondrial-derived peptide studied for cytoprotection and metabolic/longevity effects.

How it works

Signals cytoprotection and improved insulin sensitivity via mitochondrial-stress pathways; levels decline with age.

What it’s studied for

  • Studied for cellular protection
  • Reported metabolic and neuroprotective effects
  • Investigated in longevity research

Research-reported protocol

Reported research use is exploratory; protocols are not well standardised.

Route: Subcutaneous. These are amounts described in the research literature — not an instruction to administer anything.

Reconstitution — run the numbers

The same calculator the coach uses. Enter a vial size, water, and a dose to see the exact draw on a U-100 syringe.

Reconstitution

live · real math

Draw to

on a U-100 syringe

10units

2,500

mcg/mL

0.1

mL/dose

20

doses/vial

Show the math
  1. Concentration2,500 mcg/mL

    vial mg ÷ water mL × 1,000

    5 mg ÷ 2 mL × 1,000

  2. Volume per dose0.1 mL

    dose mcg ÷ concentration

    250 mcg ÷ 2,500 mcg/mL

  3. Units to draw10 units

    mL per dose × 100

    0.1 mL × 100

  4. Doses per vial20 doses

    vial mcg ÷ dose mcg (rounded down)

    5,000 mcg ÷ 250 mcg

Calculated, not guessed — the same math the app and coach use. Double-check it yourself.

The exact math, shown in the open. Full tool at the calculator.

Cautions

  • Very limited human data
  • A research chemical not approved for human use

Evidence & sources

Scientific review pending

Written by Titria Research Team.

A credentialed reviewer (PhD/PharmD) and a primary-literature citation list are still being added — we show this state honestly rather than implying a review that hasn’t happened. It means the sign-off is pending, not that the entry is unsupported. See how we rate evidence.

Search PubMed for “Humanin” →

Check the primary literature yourself — testing our labels is encouraged.

Often studied alongside

Model a Humanin protocol for your goals.

The coach interviews you, grounds every dose in this database and the calculator above, and saves a research protocol — never a hallucinated number.